An Efficient and Large Scale Process for Synthesis of Valacyclovir Dr. Reddy's Communication No. IPDO IPM-00156

V.V.N.K.V. Prasada Raju; Ravindra Vedantham; Mayur D. Khunt; Vijayavitthal T. Mathad; Pramod K. Dubey; Akula Kalyan Chakravarthy

Issue

Vol. 22 No. 5 (2010): Vol 22 Issue 5

Issue Published : February 4, 2010

An Efficient and Large Scale Process for Synthesis of Valacyclovir Dr. Reddy's Communication No. IPDO IPM-00156

V.V.N.K.V. Prasada Raju

Department of Research and Development, Integrated Product Development, Innovation Plaza, Dr. Reddy's Laboratories Ltd., Survey Nos.42, 45, 46 & 54, Bachupally, Qutubullapur, R.R. Dist-500 072, India

Ravindra Vedantham

Department of Research and Development, Integrated Product Development, Innovation Plaza, Dr. Reddy's Laboratories Ltd., Survey Nos.42, 45, 46 & 54, Bachupally, Qutubullapur, R.R. Dist-500 072, India

Mayur D. Khunt

Department of Research and Development, Integrated Product Development, Innovation Plaza, Dr. Reddy's Laboratories Ltd., Survey Nos.42, 45, 46 & 54, Bachupally, Qutubullapur, R.R. Dist-500 072, India

Vijayavitthal T. Mathad

Department of Research and Development, Integrated Product Development, Innovation Plaza, Dr. Reddy's Laboratories Ltd., Survey Nos.42, 45, 46 & 54, Bachupally, Qutubullapur, R.R. Dist-500 072, India

Pramod K. Dubey

Department of Chemistry, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad- 500 072, India

Akula Kalyan Chakravarthy

Department of Research and Development, Integrated Product Development, Innovation Plaza, Dr. Reddy's Laboratories Ltd., Survey Nos.42, 45, 46 & 54, Bachupally, Qutubullapur, R.R. Dist-500 072, India

Corresponding Author(s) : V.V.N.K.V. Prasada Raju

prasadvvnkv@drreddys.com

Asian Journal of Chemistry, Vol. 22 No. 5 (2010): Vol 22 Issue 5
Article Published : March 30, 2010

Abstract

A facile, commercially viable and large scale process is developed for an antiviral drug substance, valacyclovir hydrochloride. Several process related critical factors including organic and heavy metal impurities are efficiently addressed in this process.

Keywords

Antiviral Valacyclovir Racemization D-Isomer Metal impurities Resin

Prasada Raju, V., Vedantham, R., D. Khunt, M., T. Mathad, V., K. Dubey, P., & Kalyan Chakravarthy, A. (2010). An Efficient and Large Scale Process for Synthesis of Valacyclovir Dr. Reddy’s Communication No. IPDO IPM-00156. Asian Journal of Chemistry, 22(5), 4092–4098. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11652

Issue

Vol. 22 No. 5 (2010): Vol 22 Issue 5

An Efficient and Large Scale Process for Synthesis of Valacyclovir Dr. Reddy's Communication No. IPDO IPM-00156

Corresponding Author(s) : V.V.N.K.V. Prasada Raju

Abstract

Keywords

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