GC-MS Analysis and Antimicrobial Activity of Acalypha indica Linn.

Abstract

In this study ethanolic extract of leaves of Acalypha indica L. (Family: L. Euphorbiaceae) was tested for antimicrobial activity by disc diffusion method. It was found that the ethanolic extract of the leaves showed antimicrobial activity against both gram (+) and gram (–) bacteria. Maximal antibacterial activity was seen against Streptococcus faecalis while maximal antifungal activity was against Candida albicans. Diameter of zone of inhibition exhibited by Acalypha indica ethanolic extract against tested organisms ranged between 9-15 (in mm). GC-MS analysis of same extract revealed presence of di and triterpenes like squalene, phytol and also ethyl ester of octanoic acid all known for their antimicrobial activity. Acalypha indica. L is thus a potential medicinal plant for therapeutic use.