Synthesis and Antimicrobial Activity of Schiff Bases Derived from 2-Formylphenoxy Acetic Acid

Veenu Bala; Y.S. Chhonker; S.R. Hashim

Issue

Vol. 22 No. 5 (2010): Vol 22 Issue 5

Issue Published : February 4, 2010

Synthesis and Antimicrobial Activity of Schiff Bases Derived from 2-Formylphenoxy Acetic Acid

Veenu Bala

College of Pharmacy, Institute of Foreign Trade and Management, Moradabad-240 001, India.

Y.S. Chhonker

Pharmakinetic and Metabolism Division, Central Drug Research Institute, Lucknow-226 001, India

S.R. Hashim

College of Pharmacy, Institute of Foreign Trade and Management, Moradabad-240 001, India.

Corresponding Author(s) : Y.S. Chhonker

yashpal111@gmail.com

Asian Journal of Chemistry, Vol. 22 No. 5 (2010): Vol 22 Issue 5
Article Published : March 30, 2010

Abstract

A series of seven Schiff bases were synthesized by reacting 2-formyl-phenoxy acetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of IR and ¹H NMR. The compounds were assayed by the disc diffusion method for antibacterial activity against Staphylococcus aureus and Escherichia coli. Among the compounds tested, V₁, V₃, V₄ and V₆, exhibited good antibacterial activity, almost equal to that of ampicillin used as standard drug.

Keywords

2-Formylphenoxy acetic acid Schiff base Antibacterial activity

Bala, V., Chhonker, Y., & Hashim, S. (2010). Synthesis and Antimicrobial Activity of Schiff Bases Derived from 2-Formylphenoxy Acetic Acid. Asian Journal of Chemistry, 22(5), 3447–3452. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11568

Issue

Vol. 22 No. 5 (2010): Vol 22 Issue 5

Synthesis and Antimicrobial Activity of Schiff Bases Derived from 2-Formylphenoxy Acetic Acid

Corresponding Author(s) : Y.S. Chhonker

Abstract

Keywords

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