Determination of Trace Amounts of Cationic Surfactant Cetyl Trimethyl Ammonium Bromide by Liquid-Liquid Extraction-Spectrophotometry Method.

Abstract

This study describes a simple, sensitive and selective extractionspectrophotometric
method for the determination of trace amounts of
cationic surfactant of cetyl trimethyl ammonium bromide (CTAB), an
anti-dandruff is reporting. The CTAB-orange II ion-pair in bufferic media
is quantitatively extracted into chloroform and its absorbance is measured
at 487 nm at room temperature. The effect of different variables such as
solvent, volume of extracting solvent, volume of anionic reagent, pH,
ionic strength (NaCl 0.1 M) and shaking time is investigated and optimum
conditions for quantitative extraction of CTAB is obtained. Linear calibration
graph over the CTAB concentration range 0.5-9.0 μg mL^-1 and
regression coefficient of 0.9999 is obtained. The relative standard
deviation of eight replicate determinations of 5 μg mL^-1 of CTAB is
1.519 %. Limit of detection of the method is 0.012 μg mL^-1. The interfering
effect of a large number of diverse ions on the determination
CTAB was studied. The method is used for determination of CTAB in
the anti-dandruff shampoo and good results are obtained.