Regioselective Synthesis of Fatty Acid Esters of Methyl α-D-glucopyranoside with Dibutyltin Dimethoxide Method and Biological Test against Staphylococcus aureus and Salmonella agona
Corresponding Author(s) : Xin Lou
franklinee@hotmail.com
Asian Journal of Chemistry,
Vol. 22 No. 4 (2010): Vol 22 Issue 4
Abstract
Fatty acid esters of methyl α-D-glucopyranoside were regioselectively synthesized using dibutyltin dimethoxide (DBDM) as stannylating agent, general factors affecting regioselectivity has been examined. Comparison work indicated that DBDM has some advantage as stannylating agent over dibutyltin oxide for regioselective acylation at the 2-position of unprotected methyl α-D-glucopyranoside. Microbiological tests show that methyl 2-lauryl-α-D-glucopyranoside is effective inhibitor against gram-negative bacterial Staphylococcus aures
Keywords
Dibutyltin dimethoxide
Fatty acid esters of carbohydrates
Regioselectivity
Antibacterial
Lou, X., O’Brien, J., Henehan, G., & Cassidy, S. (2010). Regioselective Synthesis of Fatty Acid Esters of Methyl α-D-glucopyranoside with Dibutyltin Dimethoxide Method and Biological Test against Staphylococcus aureus and Salmonella agona. Asian Journal of Chemistry, 22(4), 3135–3146. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11524
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX