Synthesis, Characterization and Biological Evaluation of Some Dihydropyrimidinones
Corresponding Author(s) : S. Ganapaty
ganapatyseru@gmail.com
Asian Journal of Chemistry,
Vol. 22 No. 4 (2010): Vol 22 Issue 4
Abstract
An efficient and facile one pot synthesis of 3,4-dihydropyrimidinones (Biginelli compounds) from divergent aldehydes, β-keto esters and urea or thiourea under solvent free conditions was performed using citric acid as catalyst, resulted in promising yields. These compounds were subjected for anticancer and antiinflammatory activities which showed significant activities.
Keywords
Biginelli compounds
Citric acid
Anticancer activity
Antiinflammatory activity
Vijay, K., Ganapaty, S., & Srinivas Rao, A. (2010). Synthesis, Characterization and Biological Evaluation of Some Dihydropyrimidinones. Asian Journal of Chemistry, 22(4), 2518–2528. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11438
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