A Clean and Efficient Method for the Synthesis of 3-Aroyl-2,4,6-triaryl-4-hydroxy-1,1-cyclohexanedicarbonitriles in Water
Corresponding Author(s) : Tong-Shou Jin
jintongshou@yahoo.com.cn
Asian Journal of Chemistry,
Vol. 22 No. 3 (2010): Vol 22 Issue 3
Abstract
A clean and efficient chemistry route to the synthesis of 3-aroyl-2,4,6-triaryl-4-hydroxy-1,1- cyclohexanedicarbonitriles using hexadecyltrimethyl ammonium bromide (HTMAB) as the catalyst (5 mol %) in aqueous media is described. This method provides several advantages such as neutral conditions, high yields and simple work-up procedure. In addition, water was chosen as a green solvent.
Keywords
-Aroyl-2,4,6-triaryl-4-hydroxy-1,1-cyclohexanedi-carbonitriles
Malononitrile
1,3-Diaryl-2-propene-1-ones
Clean synthesis
(1)
Wang, A.-Q.; Jin, T.-S.; Liu, L.-B.; Cheng, Z.-L.; Li, T.-S. A Clean and Efficient Method for the Synthesis of 3-Aroyl-2,4,6-Triaryl-4-Hydroxy-1,1-Cyclohexanedicarbonitriles in Water. ajc 2010, 22, 1977-1981.
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