Improved Synthesis of Novel 2,4-Diamino-5-furfurylpyrimidine in Presence of Molecular Sieves
Corresponding Author(s) : T.K. Maity
jutkmaity@yahoo.com; rajurajapandi@yahoo.com
Asian Journal of Chemistry,
Vol. 22 No. 3 (2010): Vol 22 Issue 3
Abstract
Furfural undergoes base catalyzed condensations with b-ethoxy-propionitrile to give 3-ethoxy- 2-(furan-2-ylmethyl)acrylonitrile (3), which in turn reacts with methanolic guanidine in the presence of mole-cular sieves 3A (MS 3A) to give 2,4-diamino-5-furfurylpyrimidine (4) in fairly good yields.
Keywords
Furfural
Furfurylpyrimidine
Propionitrile
Molecular sieves
Rajapandi, R., Singh, J., & Maity, T. (2010). Improved Synthesis of Novel 2,4-Diamino-5-furfurylpyrimidine in Presence of Molecular Sieves. Asian Journal of Chemistry, 22(3), 1841–1844. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11344
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