A Facile, Chemoselective and Eco-friendly Solid Phase Synthesis of Enaminones Catalyzed by L-Proline

Raja S. Bhupathi; B. Rama Devi; P.K. Dubey

Issue

Vol. 23 No. 12 (2011): Vol 23 Issue 12

Issue Published : 29 August 2011

A Facile, Chemoselective and Eco-friendly Solid Phase Synthesis of Enaminones Catalyzed by L-Proline

Raja S. Bhupathi

Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad College of Engineering, Kukatpally, Hyderabad-500 085, India

B. Rama Devi

Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad College of Engineering, Kukatpally, Hyderabad-500 085, India

P.K. Dubey

Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad College of Engineering, Kukatpally, Hyderabad-500 085, India

Corresponding Author(s) : Raja S. Bhupathi

rs.bhupathi@gmail.com

Asian Journal of Chemistry, Vol. 23 No. 12 (2011): Vol 23 Issue 12
Article Published : 27 September 2011

Abstract

A facile and chemoselective method for the synthesis of enaminones by the reaction of aromatic primary amines with various β-ketoesters in the presence of L-proline as activator under solid phase is described. The reactions are promoted by the catalyst in short time (5-6 min) under ambient conditions, without any side products.

Keywords

Aromatic amines Enaminones L-Proline Solid phase β-Ketoesters

(1)

S. Bhupathi, R.; Rama Devi, B.; Dubey, P. A Facile, Chemoselective and Eco-Friendly Solid Phase Synthesis of Enaminones Catalyzed by L-Proline. ajc 2011, 23, 5521-5524.

Issue

Vol. 23 No. 12 (2011): Vol 23 Issue 12

A Facile, Chemoselective and Eco-friendly Solid Phase Synthesis of Enaminones Catalyzed by L-Proline

Corresponding Author(s) : Raja S. Bhupathi

Abstract

Keywords

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