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Vol. 23 No. 12 (2011): Vol 23 Issue 12

Phenolic Compounds from Tobacco Stem

Wei-Song Kong
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Zhu-Wen Cui
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Wei Liu
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Guang-Yu Yang
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Ming-Ming Miao
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Yong-Kuan Chen
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China

Corresponding Author(s) : Yong-Kuan Chen

cyk1966@163.com; ygy1110@163.com

Asian Journal of Chemistry, Vol. 23 No. 12 (2011): Vol 23 Issue 12

Abstract

A new phenolic compound (tobphenol A) together with five known phenols was isolated from the tobacco stem. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidences. The anti HIV-1 activity of tobphenol A was also evaluated. It is shown that tobphenol A has moderate anti HIV-1 activity with a therapeutic index (TI) above 128.

Keywords

Tobacco stem Phenolic compounds Tobphenol A Anti HIV-1 activity
Kong, W.-S., Cui, Z.-W., Liu, W., Yang, G.-Y., Miao, M.-M., & Chen, Y.-K. (2011). Phenolic Compounds from Tobacco Stem. Asian Journal of Chemistry, 23(12), 5308–5310. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11098
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