Synthesis of Tetraazamacrocyclic Crown Ether Ni(II) Complex and Electrochemical Study of its Interaction with DNA
Asian Journal of Chemistry,
Vol. 23 No. 11 (2011): Vol 23 Issue 11
Abstract
A tetrazamacrocyclic crown ether complex of Ni(II) with the composition [NiL](ClO4)2 (L = 5,12-dimethyl-7,14-diphenyl-1,4,8,11-tetraazamacrocyclotetradecane) was synthesized and characterized by IR spectra and elemental analysis. The mutual effects of the [NiL](ClO4)2 with DNA were studied by electrochemical method. In the presence of DNA, the redox peaks of [NiL](ClO4)2 shifted to more positive values and the peak current increased greatly. The experimental results demonstrate that the [NiL](ClO4)2 could interact with DNA by intercalation binding mode.
Keywords
Tetrazamacrocyclic crown ether
Nickel(II) complex
Synthesis
DNA
Cyclic voltammetry
Intercalation
(1)
Bi, J.-H.; Chen, Y. Synthesis of Tetraazamacrocyclic Crown Ether Ni(II) Complex and Electrochemical Study of Its Interaction With DNA. ajc 2011, 23, 5185-5186.
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