p-Dodecylbenzene Sulfonic Acid Catalyzed Simple and Efficient Synthesis of 1,8-Dioxo-decahydroacridines in Aqueous Media
Corresponding Author(s) : Sheng-Hui Li
shenghui2299@126.com; lish@hbu.edu.cn
Asian Journal of Chemistry,
Vol. 23 No. 11 (2011): Vol 23 Issue 11
Abstract
p-Dodecylbenzene sulfonic acid (DBSA)-catalyzed synthesis of new fluorinated 1,8-dioxodecahydroacridines is achieved via one-pot, three component condensation of aromatic aldehydes (1), 5,5-dimethyl-1,3-cyclohexanedione (2) and 4-fluoroaniline (3) in aqueous media. This method provides several advantages such as neutral and mild condition, high to excellent yield and simple work-up.
Keywords
Surfactant
p-Dodecylbenzene sulfonic acid
1,4-Dihydropyridine
4-Fluoroaniline
1,8-Dioxo-decahydroacridines
(1)
Li, S.-H.; Tang, C. P-Dodecylbenzene Sulfonic Acid Catalyzed Simple and Efficient Synthesis of 1,8-Dioxo-Decahydroacridines in Aqueous Media. ajc 2011, 23, 4900-4902.
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