One-Pot Preparation of 3-Hydroxymethyl 2,5-Diketopiperazine for Total Synthesis of Peticinnamin E
Corresponding Author(s) : Dequn Sun
dequn.sun@sdu.edu.cn
Asian Journal of Chemistry,
Vol. 23 No. 11 (2011): Vol 23 Issue 11
Abstract
3-Hydroxymethyl 2, 5-diketopiperazine is a structure unit of pepticinnamin E, a natural product and a bi-substrate inhibitor of FPTase. In this paper, a facile synthetic strategy was developed to prepare 3-hydroxymethyl 2, 5-diketopiperazine with high yield.
Keywords
Catalytical hydrogenation
Cyclization
2,5-Diketopiperazines analogue
Pepticinnamin E
Sun, D., Sun, L., Luo, M., & Gou, Z. (2011). One-Pot Preparation of 3-Hydroxymethyl 2,5-Diketopiperazine for Total Synthesis of Peticinnamin E. Asian Journal of Chemistry, 23(11), 5169–5170. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11071
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