One Pot Synthesis and Antibacterial Activity of 3,5-Dibromo-2,4-dihydroxy Substituted Chalcones
Corresponding Author(s) : Shiv S. Dulawat
dulawat@gmail.com
Asian Journal of Chemistry,
Vol. 23 No. 10 (2011): Vol 23 Issue 10
Abstract
In an effort to develop antibacterial agents, a series of chalcones were prepared by Claisen- Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of basic alumina as solid support reagent under microwave irradiation. The synthesized compounds were characterized by their IR, 1H NMR, mass spectral data and elemental analysis. The compounds have been screened for their antibacterial activity against S. aureus, S. fecalis, E. coli and P. mirbilis.
Keywords
Microwave
Solid-phase synthesis
Chalcone
Antibacterial activity
Devpura, A., Sharma, P., Singh Chundawat, S., Shaktawat, S., & S. Dulawat, S. (2011). One Pot Synthesis and Antibacterial Activity of 3,5-Dibromo-2,4-dihydroxy Substituted Chalcones. Asian Journal of Chemistry, 23(10), 4649–4651. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/10919
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