Phytochemical Studies of Ficus deltoidea var kunstleri

Nor Afifah Md Jamal; Kartini Ahmad; Mohd Azlan Nafiah

doi:10.14233/ajchem.2017.20502

Issue

Vol. 29 No. 7 (2017): Vol 29 Issue 7

Issue Published : May 13, 2017

This work is licensed under a Creative Commons Attribution 4.0 International License.

Phytochemical Studies of Ficus deltoidea var kunstleri

https://doi.org/10.14233/ajchem.2017.20502

Nor Afifah Md Jamal

Department of Chemistry, Faculty of Science, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia

Kartini Ahmad

Department of Chemistry, Faculty of Science, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia

Mohd Azlan Nafiah

Department of Chemistry, Faculty of Science, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia

Corresponding Author(s) : Mohd Azlan Nafiah

azlan@fsmt.upsi.edu.my

Asian Journal of Chemistry, Vol. 29 No. 7 (2017): Vol 29 Issue 7
Article Published : May 13, 2017

Abstract

Ficus deltoidea or locally known as Mas Cotek is one of the traditional medicinal plants. The aim of this work is to determine the chemical structure of isolated compounds from F. deltoidea var. kunstleri by using various spectroscopy and also by comparison with previous literature data. Chromatographic purification of hexane and dichloromethane crude extract of F. deltoidea var. kunstleri (leaves and stem barks) yielded four pure compounds viz., a-amyrin (1), lupeol (2) bergapten (3) and b-amyrin cinnamate (4) along with four mixtures; mixture of sesquiterpenes: tanacetene (5) and b-elemene (6), mixture of sterols; stigmasterol (7) and b-sitosterol (8), a mixture of triterpenes: lupeol, a,b-amyrin (9), lupenone, a,b-amyrenone (10). These compounds were identified through analysis mainly 1D and 2D NMR and also by comparison with previous studies. Even though 1, 3, 4, 5, 6, 7 and 10 are known compounds, but our best of knowledge these compounds are first time reported from this species.

Keywords

Ficus deltoidea var. kunstleri Triterpenes Sesquiterpenes Sterols

Md Jamal, N. A., Ahmad, K., & Nafiah, M. A. (2017). Phytochemical Studies of Ficus deltoidea var kunstleri. Asian Journal of Chemistry, 29(7), 1451–1454. https://doi.org/10.14233/ajchem.2017.20502

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References

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M. Nashriyah and R. Nurrul Akmar, Sains Malays., 41, 527 (2012).

E.P. Lansky and H.M. Paavilainen, Figs: The Genus Ficus, CRC Press Boca Raton, London New York (2011).

S. Suryati, N. Hazli, D. Dachriyanus and L. Md Nordin, Indo. J. Chem., 11, 67 (2011).

J. Mohd Lip, D. Nazrul Hisham, J. Arif Zaidi, Y. Musa and A. Ahmad, J. Trop. Agric. Food Sci., 37, 195 (2009).

M.H. Omar, Ph.D. Thesis, Analysis of Phytochemical in Malaysian Medicinal Plant and the Bioavailability of Dietary Hyroxycinnamates, University of Glasgow, UK (2013).

C.Y. Choo, N.Y. Sulong, F. Man and T.W. Wong, J. Ethnopharmacol., 142, 776 (2012); https://doi.org/10.1016/j.jep.2012.05.062.

L. Grison-Pigé, M. Hossaert-McKey, J.M. Greeff and J.-M. Bessière, Phytochemistry, 61, 61 (2002); https://doi.org/10.1016/S0031-9422(02)00213-3.

S. Ramamurthy, C. Kumarappan, S.R. Dharmalingam and J.K. Sangeh, Ann. Res. Rev. Biol., 4, 2357 (2014); https://doi.org/10.9734/ARRB/2014/8281.

J.H.C. de Farias, A.S. Reis, M.A.R. Araújo, M.J.A.M. Araújo, A.K.M. Assunção, J.C. Farias, E.M.S. Fialho, L.A. Silva, G.C. Costa, R.N.M. Guerra, M.N.S. Ribeiro and F.R.F. do Nascimento, Evid. Based Complement. Altern. Med., Article ID 951478 (2014); https://doi.org/10.1155/2014/951478.

H. Misbah, A.A. Aziz and N. Aminudin, BMC Complement. Altern. Med., 13, 118 (2013); https://doi.org/10.1186/1472-6882-13-118.

Z. Adam, S. Khamis, A. Ismail and M. Hamid, Res. J. Med. Plant, 4, 61 (2010); https://doi.org/10.3923/rjmp.2010.61.75.

Z. Adam, M. Hamid, A. Ismail and S. Khamis, J. Biol. Sci., 9, 796 (2009); https://doi.org/10.3923/jbs.2009.796.803.

M. Hakiman and M. Maziah, J. Med. Plants Res., 3, 120 (2009).

N. Sirisha, S. Munna, K. Sangeeta and C.M. Chetty, Int. J. Pharm. Tech. Res., 2, 2174 (2010).

H.S. Husnul, W. Ismail, Y. Harisun, M. Hanafi and S.M. Roji, J. Teknologi, 77, 19 (2015).

U. Mahmood, V.K. Kaul and B. Singh, Phytochemistry, 61, 913 (2002); https://doi.org/10.1016/S0031-9422(02)00396-5.

E.M. Gaydou, R. Faure, J.P. Bianchini, G. Lamaty, O. Rakotonirainy and R. Randriamiharisoa, J. Agric. Food Chem., 37, 1032 (1989); https://doi.org/10.1021/jf00088a048.

A. Kamboj and A.K. Saluja, Int. J. Pharm. Pharm. Sci., 3, 94 (2011).

L.L. Pierre and M.N. Moses, J. Innov. Pharm. Biol. Sci., 2, 88 (2015).

G. Negri and E. Rodrigues, Brazilian J. Pharmacog., 20, 310 (2010).

C. Chunyan, S. Bo, L. Ping, L. Jingmei and Y. Ito, J. Liq. Chromatogr. Relat. Technol., 32, 136 (2008); https://doi.org/10.1080/10826070802548747.

T. Akihisa, N. Kojima, T. Kikuchi, K. Yasukawa, H. Tokuda, E.T. Masters, A. Manosroi and J. Manosroi, J. Oleo Sci., 59, 273 (2010); https://doi.org/10.5650/jos.59.273.

M. Muller, M. Byres, M. Jaspars, Y. Kumarasamy, M. Middleton, L. Nahar and S.D. Sarker, Acta Pharm., 54, 277 (2004).

Issue

Vol. 29 No. 7 (2017): Vol 29 Issue 7

Phytochemical Studies of Ficus deltoidea var kunstleri

Corresponding Author(s) : Mohd Azlan Nafiah

Abstract

Keywords

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