Synthesis and Characterization of Pyridyl Propargyloximes

Abstract

4-Pyridiniumaldoxime and 3-pyridiniumaldoxime are synthesized by the treatment of 4- and 3- pyridinecarboxaldehydes with hydroxylamine hydrochloride, respectively. Methyl triflate salts were obtained by the treatment of methyl triflate with corresponding 4-pyridiniumaldoxime and 4-pyridinecarboxaldehyde O-propragyloxime. The reactions of 4-pyridiniumaldoxime and 3-pyridiniumaldoxime with 3-bromo-1-trimethylsilyl-1-propyne yielded the corresponding pyridinecarboxaldehyde O-propragyloximes. The structures of these products were determined by ¹H, ¹³C NMR data and X-ray structural analysis.