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Vol. 28 No. 12 (2016): Vol 28 Issue 12

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Secondary Metabolites and Antioxidant Activity of Limonium duriusculum (de Girard) Kuntze Extracts

https://doi.org/10.14233/ajchem.2016.20071
Messaoud Kerkatou
Unité de Recherche: Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université Frères Mentouri, Constantine 1, Route de Aïn El Bey, 25 000 Constantine, Algeria
Azzedine Redouane-Salah
Laboratoire de Biologie et Environnement, Université Frères Mentouri Constantine 1, 25000 Constantine, Algeria
Francisco León
Instituto de Productos Naturales y Agrobiología-C.S.I.C., Av. Astrofísico F. Sánchez 3, 38206 La Laguna, Tenerife, Spain
Ignacio Brouard
Instituto de Productos Naturales y Agrobiología-C.S.I.C., Av. Astrofísico F. Sánchez 3, 38206 La Laguna, Tenerife, Spain
Paul Mosset
Université de Rennes 1, Institut des Sciences Chimiques de Rennes, CNRS UMR 6226, 263 Avenue du Général Leclerc, CS 74205, 35042 Rennes Cedex, France
Ahmed Menad
Laboratoire de Biologie et Environnement, Université Frères Mentouri Constantine 1, 25000 Constantine, Algeria
Souad Ameddah
Laboratoire de Biologie et Environnement, Université Frères Mentouri Constantine 1, 25000 Constantine, Algeria
Samir Benayache
Unité de Recherche: Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université Frères Mentouri, Constantine 1, Route de Aïn El Bey, 25 000 Constantine, Algeria
Jaime Bermejo
Instituto de Productos Naturales y Agrobiología-C.S.I.C., Av. Astrofísico F. Sánchez 3, 38206 La Laguna, Tenerife, Spain
Fadila Benayache
Unité de Recherche: Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université Frères Mentouri, Constantine 1, Route de Aïn El Bey, 25 000 Constantine, Algeria

Corresponding Author(s) : Fadila Benayache

fbenayache@yahoo.fr

Asian Journal of Chemistry, Vol. 28 No. 12 (2016): Vol 28 Issue 12

Abstract

No reports are available in literature on phytochemical investigation of chloroform, ethyl acetate and n-butanol soluble parts of the aqueous-MeOH extract of aerial parts of Limonium duriusculum. This report identify from the extracts two new flavanones: 3b,5,6,7,8,3’,4’-heptahydroxyflavanone named duriusculin A (8) slightly contamined by its epimer, 3a,5,6,7,8,3’,4’-heptahydroxyflavanone (less than 10 %), named duriusculin B (9), together with, b-sitosterol (1); apigenin (2); methyl gallate 4-methyl ether (3); 4-O-methylgallic acid (4); methyl gallate (5); vanillic acid (6); pinoresinol (7) and apigenin 7-O-b-D-(6’’-methylglucuronide) (10). The antioxidant properties of the n-butanol extract (BEL) were investigated using three assay systems: (2,2-diphenyl-1-picrylhydrazyl radical scavenging (DPPH), lipid peroxidation (LPO) inhibition, and ferrous ion chelating (FIC) methods. This extract showed significant antioxidant activity in the lipid peroxidation inhibition and the ferrous ion chelating methods compared with standards. Compounds 2 and 10 are strongly accumulated by this plant, more than 1.6 g and 1.1 g per kg of air-dried plant material, respectively.

Keywords

Duriusculin A and B Flavonoids Phenolic compounds Limonium duriusculum Plumbaginaceae Antioxidant activity
Kerkatou, M., Redouane-Salah, A., León, F., Brouard, I., Mosset, P., Menad, A., … Benayache, F. (2016). Secondary Metabolites and Antioxidant Activity of Limonium duriusculum (de Girard) Kuntze Extracts. Asian Journal of Chemistry, 28(12), 2695–2700. https://doi.org/10.14233/ajchem.2016.20071
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