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Vol. 23 No. 8 (2011): Vol 23 Issue 8

A New Insecticidal Compound from Heliotropium indicum Linn.

A.K. Dolui
Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh-786 004, India
M. Debnath
Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh-786 004, India
B. De
Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala-799 005, India

Corresponding Author(s) : M. Debnath

manab_d@rediffmail.com

Asian Journal of Chemistry, Vol. 23 No. 8 (2011): Vol 23 Issue 8

Abstract

Earlier we reported the screening results of antifeedant activities of six fractions of methanolic extract of leaves of Heliotropium indicum. The fraction E showed highest antifeedant activity. In the present study a new compound E (2-ethyl-1,2,3,4-tetrahydro-6-hydroxymethylisoquinoline) has been isolated from fraction E. The characterization and structure elucidation of the compound E was carried out by determination of melting point, solubility, UV, HPLC, IR, NMR (1H NMR and 13C NMR) and LC-MS data. The compound E showed antifeedant activity comparable with those of standard insecticides viz., neemazal and endosulfan. The LC50 value of the compound E was found to be 2.18 %.

Keywords

Antifeedant Neemazal Endosulfan LC50 Heliotropium indicum 2-Ethyl-1,2,3,4-tetrahydro-6-hydroxymethylisoquinoline
Dolui, A., Debnath, M., & De, B. (2011). A New Insecticidal Compound from Heliotropium indicum Linn. Asian Journal of Chemistry, 23(8), 3438–3440. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/10645
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