Synthesis of 3-Ethyl Indole

Abstract

In this study, it is planned to synthesize intermediates to get β-carboline alkaloids having effective bioligical activities. In this way, we tried to synthesize 3-ethyl indole as an intermediate from simple and cheap compounds to obtain the β-carboline structure. This synthesis was carried out with a suitable method called the Fisher indole synthesis to synthese substitued indoles. That synthesis was tried for different acids and methods for acid catalyzed cyclization of buthenal phenylhydrazone to give 3-ethyl indole. FTIR, GSMS and NMR spectra were taken to determine the structural anaylsis of synthesized compounds.