Synthesis, Spectral and Biological Studies of Transition Metal Complexes of 2-(4-Nitrophenylaminocarbonyl)benzoic Acid

Abstract

In this study Cr(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes of 2-(4-nitrophenylaminocarbonyl) benzoic acid have been prepared and were characterized by physical, analytical and spectroscopic studies. On the basis of electronic spectra and magnetic susceptibility measurements in conjunction with infrared spectra, six coordinated octahedral structure has been proposed to Cr³⁺, Co³⁺ and Ni²⁺ complexes. In case of Cu²⁺ and Zn²⁺, they form four coordinated complexes. The ligand and its metal complexes have been tested for their in vitro antimicrobial activity against three bacterial strains, Mycobacterium smegmatis (gram +ve), Escherichia coli (gram - ve), Pseudomonas aeuroginosa (gram -ve) and three fungal strains, Nigrospora oryzae, Aspergillus niger and Candida albicans. The antimicrobial activities of the metal complexes were found to be more than those of 2-(4-nitrophenylaminocarbonyl)benzoic acid alone.