Microwave Synthesis of β-Uramino Crotonic Ester and its Derivatives
Corresponding Author(s) : Shahana Ehsan
shahana_organic@hotmail.com
Asian Journal of Chemistry,
Vol. 23 No. 7 (2011): Vol 23 Issue 7
Abstract
The new and rapid synthesis of β-uramino crotonic ester and its derivatives involves the condensation of ethyl acetoacetate and urea, thiourea and 1,3-dimethyl urea in presence of ethanol. These compounds are important intermediates for the synthesis of 6-methyl pyrimidinedione derivatives, which are biologically active compounds used in medicinal and pharmaceutical chemistry. The structure of the synthesized compounds has been elucidated with spectral analysis: UV, FTIR and GC-MS.
Keywords
Microwave
Condensation
6-Methyluracil
GC-MS
Ehsan, S., & Khan, B. (2011). Microwave Synthesis of β-Uramino Crotonic Ester and its Derivatives. Asian Journal of Chemistry, 23(7), 3202–3204. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/10551
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