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Vol. 23 No. 7 (2011): Vol 23 Issue 7

Trifluoromethanesulfonic Acid as an Efficient Catalyst in the Reduction of Ketimines

Jianhui Li
Department of Pharmaceutics Engineering, Xihua University, Chengdu-610039, P.R. China
Zhouyu Wang
Department of Pharmaceutics Engineering, Xihua University, Chengdu-610039, P.R. China
Zhenju Jiang
Department of Pharmaceutics Engineering, Xihua University, Chengdu-610039, P.R. China
Shengqian Jiang
Department of Pharmaceutics Engineering, Xihua University, Chengdu-610039, P.R. China

Corresponding Author(s) : Zhouyu Wang

zhouyuwang@mail.xhu.edu.cn

Asian Journal of Chemistry, Vol. 23 No. 7 (2011): Vol 23 Issue 7

Abstract

Trifluoromethanesulfonic acid was found to be highly efficient catalyst in the reduction of ketimines with Hantzsh esters as the hydrogen source. The catalyst loading could be decreased to 1 mol %. Moderate to excellent isolated yields (up to 99 %) were obtained under mild conditions.

Keywords

Trifluoromethanesulfonic acid Reduction Ketimines Hantzsh esters
(1)
Li, J.; Wang, Z.; Jiang, Z.; Jiang, S. Trifluoromethanesulfonic Acid As an Efficient Catalyst in the Reduction of Ketimines. ajc 2011, 23, 3101-3103.
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