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Vol. 23 No. 7 (2011): Vol 23 Issue 7

Synthesis and Characterization of a-Aminophosphonic Acids Containing Adenine

Du-Lin Kong
Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China ; College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China
Ming-Shu Wu
Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China ; College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China
Chang-Ri Han
Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China ; College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China
Jing-Ya Ma
Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China ; College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China
De-Hui Wan
Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China ; College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan Province, P.R. China

Corresponding Author(s) : Ming-Shu Wu

173548977@qq.com; wumingshu@126.com

Asian Journal of Chemistry, Vol. 23 No. 7 (2011): Vol 23 Issue 7

Abstract

Seven novel a-aminophosphonic acids containing adenine 2 were synthesized by the three component condensation reactions of adenine with triphenyl phosphite and aldehydes 1 in presence of acetic acid and xylene. The product structures were characterized by IR and NMR spectral data and elemental analyses.

Keywords

Adenine Mannich-type reaction α-Aminophosphonates
(1)
Kong, D.-L.; Wu, M.-S.; Han, C.-R.; Ma, J.-Y.; Wan, D.-H. Synthesis and Characterization of a-Aminophosphonic Acids Containing Adenine. ajc 2011, 23, 2871-2873.
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