Antioxidant Potential of New Methyl-4-hydroxy-2H- 1,2-benzothiazine-3-carboxylate-1,1-dioxide Derivatives
Corresponding Author(s) : Islam Ullah Khan
iukhan@gcu.edu.pk
Asian Journal of Chemistry,
Vol. 23 No. 6 (2011): Vol 23 Issue 6
Abstract
An easy synthesis of a series of N-alkyl-1,2-benzothiazine-1,1-dioxide derivatives from commercially available saccharine is reported in order to explore their antioxidant potential. The newly synthesized compounds were characterized by spectroscopic techniques (FT-IR, NMR, MS) and single crystal X-ray diffraction analyses. All the synthesized compounds were screened for their DPPH and FRAP analyses to determine their antioxidant activity.
Keywords
N-Alkylation
Antioxidant activity
: 1,2-Benzothiazine-1,1-dioxide
Crystal structure
(1)
Nadeem Arshad, M.; Ullah Khan, I.; Zia-Ur-Rehman, M.; Shafiq, M. Antioxidant Potential of New Methyl-4-Hydroxy-2H- 1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide Derivatives. ajc 2011, 23, 2801-2805.
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