Synthesis of Aniline Substituted Benzimidazole Derivatives
Corresponding Author(s) : Abhishek Tiwari
abhishekt1983@gmail.com
Asian Journal of Chemistry,
Vol. 23 No. 6 (2011): Vol 23 Issue 6
Abstract
2-Chloromethyl benzimidazole can be synthesized by the reaction of o-phenylene diamine with chloroacetic acid. This on reaction with substituted anilines in presence of ethanolic KOH gives corresponding benzimidazole derivatives. The synthesized compounds were characterized by IR, 1H NMR and mass spectral data.
Keywords
2-Chloromethyl benzimidazole
o-Phenylene diamines
Chloroacetic acid
Aniline
(1)
Tiwari, A.; Singh, A.; Tiwari, V. Synthesis of Aniline Substituted Benzimidazole Derivatives. ajc 2011, 23, 2823-2824.
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