Thermal Stability and Properties of a New CRF1 Antidepressant Compound (C22H28N4O4) from Low-Temperature Molar Heat Capacity
Wang Liang Liang1
1Department of Material Science and Engineering, China Jiliang University, Hangzhou 310018, P.R. China
2State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P.R. China
*Corresponding author: E-mail: fanmeiqiang@126.com
Mei-De Sheng2
1Department of Material Science and Engineering, China Jiliang University, Hangzhou 310018, P.R. China
2State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P.R. China
*Corresponding author: E-mail: fanmeiqiang@126.com
Jun Yao1
1Department of Material Science and Engineering, China Jiliang University, Hangzhou 310018, P.R. China
2State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P.R. China
*Corresponding author: E-mail: fanmeiqiang@126.com
Wen Qiang Sun1
1Department of Material Science and Engineering, China Jiliang University, Hangzhou 310018, P.R. China
2State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P.R. China
*Corresponding author: E-mail: fanmeiqiang@126.com
Mei-Qiang Fan1
1Department of Material Science and Engineering, China Jiliang University, Hangzhou 310018, P.R. China
2State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P.R. China
*Corresponding author: E-mail: fanmeiqiang@126.com
Asian Journal of Chemistry,
Vol. 23 No. 5 (2011): Vol 23 Issue 5
Low-temperature heat capacities of a new CRF1 antidepressant compound C22H28N4O4 were measured by a temperature modulated differential scanning calorimetry in the temperature range from T = 188 to 562 K. An obvious endothermic process took place in the temperature range of 353-372 K. The peak in the heat capacity curve was corresponding to the fusion. The experimental molar heat capacities in the temperature range of 193-353 and 372-562 K were fitted to the polynomial. The thermodynamic functions, (HT - H298.15 K) and (ST - S298.15 K), of the compound had been calculated by the numerical integral of the heat-capacity polynomial.
Liang Liang1, W., Sheng2, M.-D., Yao1, J., Qiang Sun1, W., & Fan1, M.-Q. (2011). Thermal Stability and Properties of a New CRF1 Antidepressant Compound (C22H28N4O4) from Low-Temperature Molar Heat Capacity. Asian Journal of Chemistry, 23(5), 1943–1946. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/10356
