Isolation and Characterization of Sesquiterpenoids from Daphne acutiloba Rehd.
Shun-Qin He1
1School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China
2Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
*Corresponding author: E-mail: huqiufena@yahoo.com.cn
Zhong Li1
1School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China
2Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
*Corresponding author: E-mail: huqiufena@yahoo.com.cn
Yang-Wen Ou1
1School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China
2Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
*Corresponding author: E-mail: huqiufena@yahoo.com.cn
Lan Wang1
1School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China
2Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
*Corresponding author: E-mail: huqiufena@yahoo.com.cn
Guang-Yu Yang1
1School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China
2Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
*Corresponding author: E-mail: huqiufena@yahoo.com.cn
Qiu-Fen Hu1
1School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China
2Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
*Corresponding author: E-mail: huqiufena@yahoo.com.cn
Asian Journal of Chemistry,
Vol. 23 No. 5 (2011): Vol 23 Issue 5
A new sesquiterpenoid (daphnelnoid A), together with three known, were isolated from the leaf and steam of Daphne acutiloba Rehd. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. The anti-HIV-1 activity of daphnelnoid A was also evaluated and it shows a moderate anti-HIV-1 activity with a therapeutic index above 45.2.
