One-Pot Synthesis of Dimannopyranosylbenzene (or Pyridine) and Dimannosyl-1,8-diaminooctane
Y.G. Lee1
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
J.H. Song1
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
S.H. Jung2
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
E.J. Lee1
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
E.S. Lee1
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
D.H. Lee1
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
D.I. Jung1
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
J.T. Hahn3
1Department of Chemistry, Dong-A University, Saha-Gu, Busan 604-714, South Korea
2Center for Drug Discovery Technologies, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Deajeon 305-343, South Korea
3Department of Beautycare, Young-Dong University, Chungcheongbuk-do 370-701, South Korea
*Corresponding author: Fax: +82 51 2007259; Tel: +82 51 2007249; E-mail: dijung@dau.ac.kr
Asian Journal of Chemistry,
Vol. 23 No. 5 (2011): Vol 23 Issue 5
The one-pot synthesis of divalent of mannose disaccharides, of potential use as anti-infective agents against enterobacteria infections, is described. We report one-pot synthesis of dimannopyranosylbenzenes (6, 7, 8), dimannosyl-2,6-diamino-pyridine (9) and dimannosyl- 1,8-diaminooctane (10). But the reaction of 8-(2-amino-pyridin-3-yl)-8-azabicyclo[3.2.1]octane-3-one (11) as a monoamine and D-(+)- mannose did not occur. The results implied that compound 12 is not produced due to steric hindrance of tropane ring.
