Synthesis, Characterization and Biological Activity Studies of Some N-Mannich Bases of 1-Substituted methyl-2-(substituted phenyl)benzimidazoles
Corresponding Author(s) : Rita Bamnela
ritabamnela@gmail.com
Asian Journal of Chemistry,
Vol. 23 No. 4 (2011): Vol 23 Issue 4
Abstract
The synthesis of N-Mannich bases of 1-substituted methyl-2-(substituted phenyl)benzimidazoles have been reported. The synthesized derivatives were characterized by elemental analysis and spectral data (IR and 1H NMR). All the synthesized derivatives have been evaluated for their antibacterial, anthelmintic and insecticidal activities against microbes, helminthes and insects as compared to standard drugs. All the synthesized derivatives exhibited significant to good biological activities.
Keywords
Mannich bases
Benzimidazoles
Antibacterial
Anthelmintic
Insecticidal activities
(1)
Bamnela, R.; K. Ahirwar, M.; Shrivastava, S. Synthesis, Characterization and Biological Activity Studies of Some N-Mannich Bases of 1-Substituted Methyl-2-(substituted phenyl)benzimidazoles. ajc 2010, 23, 1719-1722.
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