Synthesis and Antimicrobial Activities of Complexes of Cu(II) and Ni(II)-pyridine-2-aldoxime & Alkaline Earth Metal Salts

Abstract

The copper(II) and nickel(II)-pyridine-2-aldoxime, Ma(pyox)₂ have been used as a complex ligand for the synthesis of a number of oxygen bridged complexes of the general formula M_a(pyox)₂·M_bL₂, M_a(pyox)₂ acting as a bidentate complexing agent, coordinating through two oximino oxygens to alkaline earth metal salt (MbL₂) (where M_b = M_g, Ca, Sr or Ba; L = deprotonated 8-hydroxyquinoline or 1-nitroso-2-naphthol). The strucure has been substantiated by infrared, electronic absorption spectra and magnetic moment measurements. Most of the compounds have shown significant activity against E. coli, S. aureus and C. albicans.