Synthesis of 1-Heterocyclic Aminomethyl-3-(4'-anilino-3'-nitrobenzoyl hydrazono)- 2-indolinones as Antifilarial and CNS Active Agents
Corresponding Author(s) : S.P. Gupta
satayprakashgupta@gmail.com
Asian Journal of Chemistry,
Vol. 23 No. 4 (2011): Vol 23 Issue 4
Abstract
A series of 1-heterocyclic aminomethyl-3-(4'-anilino-3'-nitrobenzoyl hydrazono)-2-indolinones (VIa-VIl) have been synthesized and tested for their antifilarial and CNS activity. The compounds VIa, VId, VIg have exhibited 75.8, 78.2 and 70.5 % microfilaricidal activity respectively.
Keywords
1-Heterocyclic aminomethyl-3-(4'-anilino-3'-nitrobenzoyl hydrazono)-2- indolinones
Antifilarial
CNS activity
(1)
Beg, M.; Gupta, S. Synthesis of 1-Heterocyclic Aminomethyl-3-(4’-Anilino-3’-Nitrobenzoyl Hydrazono)- 2-Indolinones As Antifilarial and CNS Active Agents. ajc 2010, 23, 1569-1572.
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