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Vol. 23 No. 1 (2011): Vol 23 Issue 1

Chemical Constituents of Artocarpus kemando (Moraceae)

S.H. Teo
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
G.C.L. Ee
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
C.K. Lim
Faculty of Engineering & Science, Universiti Tunku Abdul Rahman, Jalan Genting Klang, 53300 Kuala Lumpur, Malaysia
M. Rahmani
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
C.F.J. Bong
Department of Crop Science, Faculty of Agriculture & Food Sciences, Universiti Putra Malaysia, Bintulu Campus, 97008 Bintulu, Sarawak, Malaysia

Corresponding Author(s) : G.C.L. Ee

gwen@science.upm.edu.my

Asian Journal of Chemistry, Vol. 23 No. 1 (2011): Vol 23 Issue 1

Abstract

The stem bark of Artocarpus kemando furnished 24-methylenecycloartenyl acetate (fatty acyl ester) (1) together with cycloartobiloxanthone (2). Compound 1 was obtained for the first time from this species. Structures of both compounds were determined using NMR and MS analysis. A cytotoxic study showed that the crude extract of the stem bark of Artocarpus kemando was significantly active against the HL-60 (human promyelocytic leukemia cell) and IMR-32 (human neuroblastoma cell) cell lines. This is the first report on the cyctotoxic activity of Artocarpus kemando.

Keywords

Artocapus kemando Moraceae Triterpenoid Xanthone Cytotoxicity
(1)
Teo, S.; Ee, G.; Lim, C.; Rahmani, M.; Bong, C. Chemical Constituents of Artocarpus Kemando (Moraceae). ajc 2010, 23, 74-76.
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