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Vol. 28 No. 11 (2016): Vol 28 Issue 11

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Assessment of Therapeutic Potential of Pearl Millet Iron Fortified Cookies through Animal Modeling

https://doi.org/10.14233/ajchem.2016.20084
Tayyaba Sami Ullah
Institute of Home & Food Sciences, Government College University, Faisalabad-38000, Pakistan
Farhan Saeed
Institute of Home & Food Sciences, Government College University, Faisalabad-38000, Pakistan
Nighat Bhatty
Department of Food Science, Government College Women University, Faisalabad-38000, Pakistan
Muhammad Umair Arshad
Institute of Home & Food Sciences, Government College University, Faisalabad-38000, Pakistan
Faqir Muhammad Anjum
Institute of Home & Food Sciences, Government College University, Faisalabad-38000, Pakistan
Muhammad Afzaal
Institute of Home & Food Sciences, Government College University, Faisalabad-38000, Pakistan
Azmat Ullah
Department of Food Science and Human Nutrition, University of Veterinary and Animal Sciences, Lahore-54000, Pakistan
Muhammad Aamir
Department of Food Science and Technology, Kasetsart University, Bangkok, 10900, Thailand

Corresponding Author(s) : Muhammad Aamir

aami.bajwa@wsu.edu

Asian Journal of Chemistry, Vol. 28 No. 11 (2016): Vol 28 Issue 11

Abstract

Diet diversification and food fortification are successful strategies to combat micronutrient deficiencies and allied disorders. The current research study is an attempt to assess the therapeutic evaluation of pearl millet (Pennisetum glaucum L.) based iron-fortified cookies to combat anemia. In the first phase, pearl millet was characterized for nutritional composition through respective methods. Moreover, iron fortified cookies were prepared that composed of composite flour of pearl millet and wheat flour with the addition of iron fortificants i.e. NaFeEDTA and FeSO4. In 2nd phase, the efficacy study was accomplished through animal modeling. Results showed that anemia was significantly reduced by both pearl millet iron fortified cookies treatments. In addition, pronounced increase in hemoglobin (Hb) level was examined for pearl millet iron fortified cookies with NaFeEDTA than pearl millet iron fortified cookies fortified with FeSO4. The parameters for anemia study including red blood cell, hemoglobin and hematocrit level showed improvement both in anemic and non-anemic rats studies. Conclusively, the results from the current study revealed that NaFeEDTA salt is a better option for fortification than FeSO4. In the nutshell, pearl millet composite flour with iron fortification (NaFeEDTA) should be included in dietary patterns for controlling anemia.

Keywords

Malnutrition Iron deficiency anemia Fortification Diet-diversification Pearl millet
Ullah, T. S., Saeed, F., Bhatty, N., Arshad, M. U., Anjum, F. M., Afzaal, M., … Aamir, M. (2016). Assessment of Therapeutic Potential of Pearl Millet Iron Fortified Cookies through Animal Modeling. Asian Journal of Chemistry, 28(11), 2545–2548. https://doi.org/10.14233/ajchem.2016.20084
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