Synthesis, Spectral Characterization and Antimicrobial Activities of Unsymmetrical Schiff Base Metal Complexes

Abstract

Six new unsymmetrical Schiff base metal complexes of VO²⁺, Ni²⁺ and Cu²⁺ have been synthesized from 2-hydroxynaphthaldehyde, 5-bromo/chlorosalicylaldehyde and o-phenylenediamine. Metal ions coordinate in a tetradentate manner with this N₂O₂ donor ligand, which are characterized by elemental analysis, molar conductance, IR and electronic spectral studies. The elemental analysis suggests that the stoichiometry to be 1:1 (metal:ligand). The molar conductivity values suggest that the complexes are non-electrolytic in nature. The ligands (H₂L), in comparison to its metal complexes are screened for its antibacterial activity against two gram negative and two gram positive microorganisms using well diffusion method. The activity data shows that metal complexes have antibacterial activity more than the parent Schiff bases and standard streptomycin because of chelation.