Studies of Fe(III) and Mn(II) Complexes of Valerohydroxamic Acid and Isovalerohydroxamic Acid

Abstract

The Fe³⁺ and Mn²⁺ complexes of valerohydroxamic and isovalerohydroxamic acids were prepared with good yield. Infrared studies of the isolated solid indicates chelation via ketonic oxygen. The solution studies of the systems, reveals the formation of a single specie, with a 1:2 and 1:3 metal-ligands ratios for Mn²⁺ and Fe³⁺ systems, respectively. The electronic studies of the complexes indicates a d-d and ⁶A_1g® ⁴A_1g, ⁴E_g transitions for Mn²⁺ and Fe³⁺ complexes, respectively. They do not show any activity towards the test organisms, with exception of iron(III) valerohydroxamate, which shows partial activity against Staphylocoacus aureus (Sa) and Candida albicans (Ca) at a dosage of 1000 μs/mL.