Synthesis and Biological Evaluation of Some 3,5-Dibromo-4-hydroxy Enoness

Abstract

Enones having an a,b-unsaturated carbonyl systems are important as Michael acceptors and constitute an important class of biologically active compounds. Enones are one of the most versatile synthons for various chemical transformations leading to the synthesis of several biodynamic heterocyclic compounds. Therefore, the chemistry of synthetic enones is most dynamic and challenging area embracing a vast spectrum of advances of both theoretical and practical relevance. In view of this, in the present paper synthesis of some 3,5-dibromo-4-hydroxyphenyl enones are reported along with their herbicidal, fungicidal, insecticidal, animal health and antibacterial activities. Some of the compounds showed promising biological activities.