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New Chemical Constituent from Panax ginseng Roots
Corresponding Author(s) : Ateeque Ahmad
Asian Journal of Chemistry,
Vol. 26 No. 22 (2014): Vol 26 Issue 22
Abstract
One new constituent lanost-24-en-3b-ol-3b-D-xylopyranosyl-(2'®1'')-b-D-xylopyranoside has been isolated and identified from the methanol extract of heat processed roots of Panax ginseng. The structure of compound was elucidated with the help of 600 MHz NMR using 1D and 2D spectral methods viz., 1H and 13C aided by FAB/MS and IR spectroscopy.
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- J. Shoji, in eds.: H. Oura, A. Kumagaki, S. Shibata, K. Takagi, Panax Ginseng, Kyoritsu Shuppan, Tokyo, pp. 10-41 (1981).
- H. Besso, R. Kasai, Y. Saruwatari, T. Fuwa and O. Tanaka, Chem. Pharm. Bull. (Tokyo), 30, 2380 (1982); doi:10.1248/cpb.30.2380.
- I. Kitagawa, T. Taniyama, T. Hayashi and M. Yoshikawa, Chem. Pharm. Bull. (Tokyo), 31, 3353 (1983); doi:10.1248/cpb.31.3353.
- A.S. Attele, Y.-P. Zhou, J.-T. Xie, J.A. Wu, L. Zhang, L. Dey, W. Pugh, P.A. Rue, K.S. Polonsky and C.-S. Yuan, Diabetes, 51, 1851 (2002); doi:10.2337/diabetes.51.6.1851.
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- N. Fukuyama, M. Shibuya and Y. Orihara, Chem. Pharm. Bull. (Tokyo), 60, 377 (2012); doi:10.1248/cpb.60.377.
- H. Matsunaga, M. Katano, H. Yamamoto, H. Fujito, M.K. Mori and T. Takata, Chem. Pharm. Bull. (Tokyo), 38, 3480 (1990); doi:10.1248/cpb.38.3480.
- M.C. Rho, H.S. Lee, S.W. Lee, J.S. Chang, O.E. Kwon, M.Y. Chung and Y.K. Kim, J. Agric. Food Chem., 53, 919 (2005); doi:10.1021/jf040370x.
- B.H. Han, in ed.: H.W. Base, Korean Ginseng, Korean Ginseng Research Institute, Seoul, pp. 77-108 (1978).
- O. Tanaka and R. Kasai, in eds.: W. Herz, H. Griesebach, G.W. Kirby and Ch. Tamm, Progress in the Chemistry of Organic Natural Products, Springer-Verlag Vienna, New York, pp. 1-76 (1984).
- I. Kitagawa, T. Taniyama, M. Yoshikawa, Y. Ikenishi and Y. Nakagawa, Chem. Pharm. Bull. (Tokyo), 37, 2961 (1989); doi:10.1248/cpb.37.2961.
- D.Y. Kim, J. Korean Agric. Chem. Soc., 16, 60 (1973).
- T.K. Takaku, K.Y. Kameda, K. Matsuura, H. Sekiya and H. Okuda, Planta Med., 56, 27 (1990); doi:10.1055/s-2006-960877.
- S.D. Lee and H. Okuda, Korean J. Ginseng Sci., 14, 67 (1990).
- J.H. Do, H.O. Lee, S.K. Lee, K.B. Noh, S.D. Lee and K.S. Lee, Korean J. Ginseng Sci., 17, 145 (1993).
- K.Y. Nam, Contemporary Korean Ginseng: Chemical Constituents and Biological Activity; Korea Ginseng and Tobacco Research Institute: Daejeon, Korea, Chap. 3, pp. 56-134 (1996).
- T.K. Yun, Y.S. Lee, Y.H. Lee, S.I. Kim and H. Yung, J. Korean Med. Sci., 16(Suppl), S6 (2001).
- K. Hirakura, K. Morita, M.K. Nakajima, Y. Ikeya and H. Mitsuhashi, Phytochemistry, 31, 899 (1992); doi:10.1016/0031-9422(92)80036-E.
- S.C. Shim, S.K. Chang, C.W. Hur and C.K. Kim, Phytochemistry, 26, 2849 (1987); doi:10.1016/S0031-9422(00)83603-1.
- I.H. Park, N.Y. Kim, S.B. Han, J.M. Kim, S.W. Kwon, H.J. Kim, M.K. Park and J.H. Park, Arch. Pharm. Res., 25, 428 (2002); doi:10.1007/BF02976595.
- J.H. Ryu, J.H. Park, J.H. Eun, D.H. Jung and D.H. Sohn, Phytochemistry, 44, 931 (1997); doi:10.1016/S0031-9422(96)00661-9.
- N.I. Baek, D.S. Kim, Y.H. Lee, J.D.C. Park, C.B. Lee and S.I. Kim, Planta Med., 62, 86 (1996); doi:10.1055/s-2006-957816.
- I.M. Chung, M.Y. Kim, P. Nagella, Y.P. Hong and A. Ahmad, Asian J. Chem., 25, 1086 (2013).
- I.M. Chung and M. Ali, Asian J. Chem., 25, 4667 (2013).
- S.B. Mahato and A.P. Kundu, Phytochemistry, 37, 1517 (1994); doi:10.1016/S0031-9422(00)89569-2.
- M. Ali, Techniques in Terpenoid Identifications; Birla Publishers: New Delhi, pp. 91–94 (2001).
- D.Q. Yu and J.S. Yang, Handbook of Analytical Chemistry: Analysis of NMR Spectra, Chemical Industry Press, Beijing, edn. 2, Volume 7 (1999).
References
J. Shoji, in eds.: H. Oura, A. Kumagaki, S. Shibata, K. Takagi, Panax Ginseng, Kyoritsu Shuppan, Tokyo, pp. 10-41 (1981).
H. Besso, R. Kasai, Y. Saruwatari, T. Fuwa and O. Tanaka, Chem. Pharm. Bull. (Tokyo), 30, 2380 (1982); doi:10.1248/cpb.30.2380.
I. Kitagawa, T. Taniyama, T. Hayashi and M. Yoshikawa, Chem. Pharm. Bull. (Tokyo), 31, 3353 (1983); doi:10.1248/cpb.31.3353.
A.S. Attele, Y.-P. Zhou, J.-T. Xie, J.A. Wu, L. Zhang, L. Dey, W. Pugh, P.A. Rue, K.S. Polonsky and C.-S. Yuan, Diabetes, 51, 1851 (2002); doi:10.2337/diabetes.51.6.1851.
W.M. Kim, J.M. Kim, S.B. Han, S.K. Lee, N.D. Kim, M.K. Park, C.K. Kim and J.H. Park, J. Nat. Prod., 63, 1702 (2000); doi:10.1021/np990152b.
N. Fukuyama, M. Shibuya and Y. Orihara, Chem. Pharm. Bull. (Tokyo), 60, 377 (2012); doi:10.1248/cpb.60.377.
H. Matsunaga, M. Katano, H. Yamamoto, H. Fujito, M.K. Mori and T. Takata, Chem. Pharm. Bull. (Tokyo), 38, 3480 (1990); doi:10.1248/cpb.38.3480.
M.C. Rho, H.S. Lee, S.W. Lee, J.S. Chang, O.E. Kwon, M.Y. Chung and Y.K. Kim, J. Agric. Food Chem., 53, 919 (2005); doi:10.1021/jf040370x.
B.H. Han, in ed.: H.W. Base, Korean Ginseng, Korean Ginseng Research Institute, Seoul, pp. 77-108 (1978).
O. Tanaka and R. Kasai, in eds.: W. Herz, H. Griesebach, G.W. Kirby and Ch. Tamm, Progress in the Chemistry of Organic Natural Products, Springer-Verlag Vienna, New York, pp. 1-76 (1984).
I. Kitagawa, T. Taniyama, M. Yoshikawa, Y. Ikenishi and Y. Nakagawa, Chem. Pharm. Bull. (Tokyo), 37, 2961 (1989); doi:10.1248/cpb.37.2961.
D.Y. Kim, J. Korean Agric. Chem. Soc., 16, 60 (1973).
T.K. Takaku, K.Y. Kameda, K. Matsuura, H. Sekiya and H. Okuda, Planta Med., 56, 27 (1990); doi:10.1055/s-2006-960877.
S.D. Lee and H. Okuda, Korean J. Ginseng Sci., 14, 67 (1990).
J.H. Do, H.O. Lee, S.K. Lee, K.B. Noh, S.D. Lee and K.S. Lee, Korean J. Ginseng Sci., 17, 145 (1993).
K.Y. Nam, Contemporary Korean Ginseng: Chemical Constituents and Biological Activity; Korea Ginseng and Tobacco Research Institute: Daejeon, Korea, Chap. 3, pp. 56-134 (1996).
T.K. Yun, Y.S. Lee, Y.H. Lee, S.I. Kim and H. Yung, J. Korean Med. Sci., 16(Suppl), S6 (2001).
K. Hirakura, K. Morita, M.K. Nakajima, Y. Ikeya and H. Mitsuhashi, Phytochemistry, 31, 899 (1992); doi:10.1016/0031-9422(92)80036-E.
S.C. Shim, S.K. Chang, C.W. Hur and C.K. Kim, Phytochemistry, 26, 2849 (1987); doi:10.1016/S0031-9422(00)83603-1.
I.H. Park, N.Y. Kim, S.B. Han, J.M. Kim, S.W. Kwon, H.J. Kim, M.K. Park and J.H. Park, Arch. Pharm. Res., 25, 428 (2002); doi:10.1007/BF02976595.
J.H. Ryu, J.H. Park, J.H. Eun, D.H. Jung and D.H. Sohn, Phytochemistry, 44, 931 (1997); doi:10.1016/S0031-9422(96)00661-9.
N.I. Baek, D.S. Kim, Y.H. Lee, J.D.C. Park, C.B. Lee and S.I. Kim, Planta Med., 62, 86 (1996); doi:10.1055/s-2006-957816.
I.M. Chung, M.Y. Kim, P. Nagella, Y.P. Hong and A. Ahmad, Asian J. Chem., 25, 1086 (2013).
I.M. Chung and M. Ali, Asian J. Chem., 25, 4667 (2013).
S.B. Mahato and A.P. Kundu, Phytochemistry, 37, 1517 (1994); doi:10.1016/S0031-9422(00)89569-2.
M. Ali, Techniques in Terpenoid Identifications; Birla Publishers: New Delhi, pp. 91–94 (2001).
D.Q. Yu and J.S. Yang, Handbook of Analytical Chemistry: Analysis of NMR Spectra, Chemical Industry Press, Beijing, edn. 2, Volume 7 (1999).