Issue

Vol. 28 No. 9 (2016): Vol 28 Issue 9

Copyright (c) 2016 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Antioxidant Activity of Flavonoids on Superoxide Anion Free Radical (O2•−)

https://doi.org/10.14233/ajchem.2016.19933
Xin-Ming Lei
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Ge-Wei Liu
The Affiliated High School of Longdong University, QingYang 745000, Gansu Province, P.R. China
Guo-Ying Wang
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Gao-Feng Shi
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Tai-Chun Guo
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Fei-Yun Li
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China

Corresponding Author(s) : Guo-Ying Wang

gywangcn@126.com

Asian Journal of Chemistry, Vol. 28 No. 9 (2016): Vol 28 Issue 9

Abstract

The objective of the present investigation was to study the antioxidant capacity of quercetin, catechin, luteolin, scutellarein, genistein and baicalein on superoxide anion free radical (O2•−) and explored the relationship between their structure and clearing ability. In this paper, the antioxidant capacity and IC50 were determined by cyclic voltammetry. Result showed that six kinds of flavonoids have strong scavenging ability to O2•−. The removal ability turn out to be quercetin (IC50, 0.4659) > catechin (IC50, 0.5867) > luteolin (IC50, 0.7085) > scutellarein (IC50, 1.3066) > baicalein (IC50, 1.4836) > genistein (IC50, 1.7695). The results indicate that clearing ability was closely related to their structure. The number and location of hydroxyl in A, B, C rings, meta-hydroxy, pro-hydroxyl and double bond of the formatting are all important influencing factors to antioxidant activity.

Keywords

Flavonoids Antioxidant activity Cyclic voltammetry Antioxidant capacity
Lei, X.-M., Liu, G.-W., Wang, G.-Y., Shi, G.-F., Guo, T.-C., & Li, F.-Y. (2016). Antioxidant Activity of Flavonoids on Superoxide Anion Free Radical (O2•−). Asian Journal of Chemistry, 28(9), 2082–2084. https://doi.org/10.14233/ajchem.2016.19933
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. S.R.J. Maxwell, Drugs, 49, 345 (1995); doi:10.2165/00003495-199549030-00003.
  2. B. Halliwell, J. Neutrochem., 59, 1609 (1992); doi:10.1111/j.1471-4159.1992.tb10990.x.
  3. C.S. Yang, P.J. Tsai, J.P. Wu, N.N. Lin, S.T. Chou and J.S. Kuo, J. Chromatogr. B, 693, 257 (1997); doi:10.1016/S0378-4347(97)00033-9.
  4. R Tang, R X Fan, 34, 435 (1999).
  5. Y.N. Hou, X.Y. Zhu and G.F. Cheng, Acta Pharm. Sin., 35, 161 (2000).
  6. J.W. Chen, T.X. Hu and D.Y. Zhu, J. Chin. Pharm., 37, 57 (2001).
  7. J.H. Zhao, Y. Liang and D.Y. Yan, J. North China Univ. Technol., 13, 32 (2001).
  8. S. Chevion, M.A. Roberts and M. Chevion, Free Radic. Biol. Med., 28, 860 (2000); doi:10.1016/S0891-5849(00)00178-7.
  9. 9 B. Yang, A. Kotani, K. Arai and F. Kusu, Anal. Sci., 17, 599 (2001); doi:10.2116/analsci.17.599.
  10. L.M. Magalhaes, M.A. Segundo, S. Reis and J.L.F.C. Lima, Anal. Chim. Acta, 613, 1 (2008); doi:10.1016/j.aca.2008.02.047.
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 0