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Vol. 25 No. 4 (2013): Vol 25 Issue 4

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Synthesis, Characterization and Antibacterial Activity of Co(II), Cu(II) and Zn(II) Complexes Derived from 4-Methylthiosemicarbazide and 5-Nitrosalicylaldehyde

https://doi.org/10.14233/ajchem.2013.13272
Gai Zhang
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Shaanxi Key Laboratory of Physico-Inorganic Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P.R. China ; School of Materials and Chemical Engineering, Xi'an Technological University, Xi'an 710032, P.R. China
Yingying Li
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Shaanxi Key Laboratory of Physico-Inorganic Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P.R. China
Xun Feng
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Shaanxi Key Laboratory of Physico-Inorganic Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P.R. China
Ronglan Zhang
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Shaanxi Key Laboratory of Physico-Inorganic Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P.R. China
Jianshe Zhao
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Shaanxi Key Laboratory of Physico-Inorganic Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P.R. China

Corresponding Author(s) : Jianshe Zhao

jszhao@nwu.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 4 (2013): Vol 25 Issue 4

Abstract

The reaction of cobalt(II), copper(II) and zinc(II) with NS donor ligand derived by condensing 5-nitrosalicylaldehyde with 4-methylthiosemicarbazide have been carried out. The structure of the NS donor ligand was determined by single-crystal X-ray diffraction analysis. The crystal belongs to monoclinic system, space group C2/c, with cell parameters: a = 1.31165(5), b = 0.71876(3), c = 2.38370(7) nm, a = 90º, b = 90.855º(3), g = 90º, V = 2.24701(14) nm3, Z = 8, F(000) = 1056, Mr =254.27, Dc =1.503 g/cm3, μ(MoKa) = 0.291 mm-1, R1 = 0.0462, wR2 = 0.1202. The analysis of the crystal structure indicates that the complex has a three-dimensional network structure, which is formed by hydrogen bonds and electrostatic interaction. The ligand and its metal complexes are determined by elemental analysis, infrared spectra, UV spectra and the antibacterial activity. It is concluded that the thionic sulphur and Shiff base nitrogen atom of ligand are bonded to the metal ion. The results of antibacterial activity show that all of the ligand and the complexes can restrain the activity of bacteria.

Keywords

Sulf-schiff base complexes NS Donor ligand Crystal structure Antibacterial activity
Zhang, G., Li, Y., Feng, X., Zhang, R., & Zhao, J. (2012). Synthesis, Characterization and Antibacterial Activity of Co(II), Cu(II) and Zn(II) Complexes Derived from 4-Methylthiosemicarbazide and 5-Nitrosalicylaldehyde. Asian Journal of Chemistry, 25(4), 2003–2006. https://doi.org/10.14233/ajchem.2013.13272
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