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Vol. 25 No. 11 (2013): Vol 25 Issue 11

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Investigation on the Influence and Interaction Effect of Phytosterols on the Polycyclic Aromatic Hydrocarbons Delivery in Tobacco Based on Uniform Design

https://doi.org/10.14233/ajchem.2013.14283
You Du
Key Lab of Green Chemistry and Technology, Ministry of Education; College of Chemistry, Sichuan University, Chengdu 610064, P.R. China
Fang Xue
Technology R & D Center, China Tobacco Chuanyu Industrial Corporation, Chengdu 610066, P.R. China
Hailong Liu
Key Lab of Green Chemistry and Technology, Ministry of Education; College of Chemistry, Sichuan University, Chengdu 610064, P.R. China
Fengcheng Shi
Technology R & D Center, China Tobacco Chuanyu Industrial Corporation, Chengdu 610066, P.R. China
Ya Dai
Technology R & D Center, China Tobacco Chuanyu Industrial Corporation, Chengdu 610066, P.R. China
Dongliang Li
Technology R & D Center, China Tobacco Chuanyu Industrial Corporation, Chengdu 610066, P.R. China
Hua Chen
Technology R & D Center, China Tobacco Chuanyu Industrial Corporation, Chengdu 610066, P.R. China

Corresponding Author(s) : Fang Xue

xuefang@pride56.com

Asian Journal of Chemistry, Vol. 25 No. 11 (2013): Vol 25 Issue 11

Abstract

In this study, the impact of four free phytosterols (cholesterol, stigmasterol, b-sitosterol and campesterol) on the delivery of 15 polycyclic aromatic hydrocarbons in tobacco was analyzed by GC/MS, the experiments were designed and carried out basing on uniform design and the results were analyzed by a second-order polynomial stepwise regression model. With regression analysis, the results highlight that those four free phytosterols as well as their interaction effect significantly influenced the delivery of polycyclic aromatic hydrocarbons and there may existed an obvious linear relationship. The analysis results of benzo[a]pyrene indicated that cholesterol, stigmasterol and campesterol have a positive influence on the delivery of benzo[a]pyrene while the interaction effect between cholesterol and campesterol, between stigmasterol and campesterol, between b-sitosterol and campesterol have a negative influence on the delivery of benzo[a]pyrene.

Keywords

Phytosterols Polycyclic aromatic hydrocarbons Uniform design Regression analysis
Du, Y., Xue, F., Liu, H., Shi, F., Dai, Y., Li, D., & Chen, H. (2013). Investigation on the Influence and Interaction Effect of Phytosterols on the Polycyclic Aromatic Hydrocarbons Delivery in Tobacco Based on Uniform Design. Asian Journal of Chemistry, 25(11), 6125–6129. https://doi.org/10.14233/ajchem.2013.14283
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