Synthesis, Spectral and Antibacterial Studies of Some Hg(II) Chelates of Azo Dyes derived from 4-Amino-2,3-Dimethyl-1-Phenyl Pyrazol-5-one

Abstract

Eleven new complexes of three azo dyes, 2,3-dimethyl-1-phenyl-4-(2-hydroxy-5-methyl phenyl azo)pyrazol-5-one (CAAPH), 2,3-dimethyl-1-phenyl-4-(2-hydroxy-5-chlorophenylazo)pyrazol-5-one (CPAAPH) and 2,3-dimethyl-1-phenyl-4-(2-hydroxy-5-nitrophenylazo)pyrazol-5-one (NPAAPH, derived from 4-amino antipyrine having the compositions [Hg(LH)X₂], [Hg(L'H)X₂] or [Hg(L"H)X₂] (LH = CAAPH, L'H = CPAAPH, L"H = NPAAPH and X = Cl, Br, I or NO₃) have been synthesized and characterized by elemental analysis, magnetic moment and conductance measurement, IR and ¹HNMR spectral studies. The ligand NPAAPH and one of its complexes have been screened for their antibacterial activity against gram-positive and gram-negative bacteria. The ligands behave as neutral bidentate chelating agents. The complexes are found to be monomeric and neutral with a tetrahedral geometry.