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Vol. 33 No. 3 (2021): Vol 33 Issue 3

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GC-MS Chemical Constituents and in vitro Activities of the Oil Extract of Euryops brevipapposus Leaves used Traditionally for the Management of Some Diseases

https://doi.org/10.14233/ajchem.2021.23066
Abiodun Atinuke Adegborioye
Department of Biology, School of Science and Technology, Sefako Makgatho Health Sciences University, Molotlegi Street, Ga-Rankuwa 0204, Pretoria, South Africa
Oyinlola Oluwunmi Olaokun
Department of Biology, School of Science and Technology, Sefako Makgatho Health Sciences University, Molotlegi Street, Ga-Rankuwa 0204, Pretoria, South Africa
Benson Chuks Iweriebor
Department of Biology, School of Science and Technology, Sefako Makgatho Health Sciences University, Molotlegi Street, Ga-Rankuwa 0204, Pretoria, South Africa
Larry Chikwulu Obi
Department of Biology, School of Science and Technology, Sefako Makgatho Health Sciences University, Molotlegi Street, Ga-Rankuwa 0204, Pretoria, South Africa

Corresponding Author(s) : Benson Chuks Iweriebor

benvida2004@yahoo.com

Asian Journal of Chemistry, Vol. 33 No. 3 (2021): Vol 33 Issue 3

Abstract

Euryops brevipapposus (Asteraceae) is a medicinal plant of a local community utilized traditionally for its recognized effectiveness in managing non-communicable diseases, especially asthma. The traditional use of E. brevipapposus lacks scientific evidence and the increased burden of asthma makes confirming this claim paramount. The study characterized by GC-MS the bioactive compounds of E. brevipapposus essential oil (EbO) extracted with Clevenger apparatus. The antibacterial efficacy and antioxidant activity by free radical scavenging ability were investigated in vitro using standard methods. A strong antioxidant IC50 value of 6.71 × 10-7 mg/mL of oil was obtained for DPPH. The antibacterial activity against Escherichia coli and Vibrio spp. (MIC value of 0.055 mg/mL) was superior. GC-MS analysis of EbO showed α-phellandrene, α-pinene, germacrene D, β-pinene, β-mycrene, (E)-β-ocimene and bicyclogermacrene as the major compounds. The antioxidant and antibacterial potentials of E. brevipapposus may justify the therapeutic claims and local usage of this plant.

Keywords

Antibacterial Antioxidant Asteraceae Euryops Essential oil GC-MS
Atinuke Adegborioye, A., Oluwunmi Olaokun, O., Chuks Iweriebor, B., & Chikwulu Obi, L. (2021). GC-MS Chemical Constituents and in vitro Activities of the Oil Extract of Euryops brevipapposus Leaves used Traditionally for the Management of Some Diseases. Asian Journal of Chemistry, 33(3), 677–685. https://doi.org/10.14233/ajchem.2021.23066
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References
  1. United Nations, Political Declaration of the High-Level Meeting of the General Assembly on the Prevention and Control of Non-Communicable Diseases, United Nations: New York, September 16 (2011).
  2. The International Union against Tuberculosis and Lung Disease (IUATLD), Political Declaration of the High-Level Meeting of the General Assembly on the Prevention and Control of Non-Communicable Diseases, United Nations: New York, September 16 (2011)
  3. L.G. Wood, J.L. Simpson, P.M. Hansbro and P.G. Gibson, Free Radic. Res., 44, 146 (2010); https://doi.org/10.3109/10715760903362576
  4. H. Sugiura and M. Ichinose, Antioxid. Redox Signal., 10, 785 (2008); https://doi.org/10.1089/ars.2007.1937
  5. M.A. Riedl and A.E. Nel, Curr. Opin. Allergy Clin. Immunol., 8, 49 (2008); https://doi.org/10.1097/ACI.0b013e3282f3d913
  6. K. Skarbez, Y. Priestley, M. Hoepf and S.B. Koevary, Expert Rev. Ophthalmol., 5, 557 (2010); https://doi.org/10.1586/eop.10.44
  7. U.M. Sahiner, E. Birben, S. Erzurum, C. Sackesen and O. Kalayci, World Allergy Organ. J., 4, 151 (2011); https://doi.org/10.1097/WOX.0b013e318232389e
  8. A. Nadeem, N.O. Alharbi, H. Vliagoftis, M. Tyagi, S.F. Ahmad and M.M. Sayed Ahmed, Immunology, 145, 391 (2015); https://doi.org/10.1111/imm.12453
  9. S.H. Wedes, S.B. Khatri, R. Zhang, W. Wu, S.A. Comhair, S. Wenzel, W.G. Teague, E. Israel, S.C. Erzurum and S.L. Hazen, Clin. Transl. Sci., 2, 112 (2009); https://doi.org/10.1111/j.1752-8062.2009.00095.x
  10. C. Alves, J. Casqueiro and J. Casqueiro, Indian J. Endocrinol. Metab., 16, S27 (2012); https://doi.org/10.4103/2230-8210.94253
  11. B. Li, Q.L. Luo, M. Nurahmat, H.L. Jin, Y.J. Du, X. Wu, Y.-B. Lv, J. Sun, M. Abduwaki, W.-Y. Gong and J.-C. Dong, Evid. Based Complement. Alternat. Med., 2013, 658364 (2013); https://doi.org/10.1155/2013/658364
  12. J. Bousquet, E. Mantzouranis, A.A. Cruz, N. Aït-Khaled, C.E. BaenaCagnani, E.R. Bleecker, C.E. Brightling, P. Burney, A. Bush, W.W. Busse, T.B. Casale, M. Chan-Yeung, R. Chen, B. Chowdhury, K.F. Chung, R. Dahl, J.M. Drazen, L.M. Fabbri, S.T. Holgate, F. Kauffmann, T. Haahtela, N. Khaltaev, J.P. Kiley, M.R. Masjedi, Y. Mohammad, P.O’Byrne, M.R. Partridge, K.F. Rabe, A. Togias, C. van Weel, S. Wenzel, N. Zhong and T. Zuberbier, J. Allergy Clin. Immunol., 126, 926 (2010); https://doi.org/10.1016/j.jaci.2010.07.019
  13. P. Tiwari, A.K. Tamrakar, R. Ahmad, M.N. Srivastava, R. Kumar, V. Lakshmi and A.K. Srivastava, Med. Chem. Res., 17, 74 (2008); https://doi.org/10.1007/s00044-007-9038-3
  14. N. Pandey, S.K. Yadav and K. Mathur, World J. Pharm. Pharm. Sci., 5, 481 (2015).
  15. Q.W. Shi, L.G. Li, C.H. Huo, M.L. Zhang and Y.F. Wang, Chin. Tradit. Herbal Drugs, 41, 1583 (2010).
  16. J. Mittal, M.M. Sharma and A. Batra, J. Med. Plant Stud., 2, 32 (2014).
  17. M. Hyldgaard, T. Mygind and R.L. Meyer, Front. Microbiol., 3, 12 (2012); https://doi.org/10.3389/fmicb.2012.00012
  18. C.C.M.P. Santos, M.S. Salvadori, V.G. Mota, L.M. Costa, A.A. de Almeida, G.A. de Oliveira, J.P. Costa, D.P. de Sousa, R.M. de Freitas and R.N. de Almeida, Neurosci. J., 2013, 949452 (2013); https://doi.org/10.1155/2013/949452
  19. A.A. Anderberg, B.G. Baldwin, R.G. Bayer, J. Breitwieser, C. Jeffrey, M.O. Dillon, P. Eldenäs, V. Funk, N. Garcia-Jacas, D.J.N. Hind, P.O. Karis, H.W. Lack, G. Nesom, B. Nordenstam, Ch. Oberprieler, J.L. Panero, C. Puttock, H. Robinson, T.F. Stuessy, A. Susanna, E. Urtubey, R. Vogt, J. Ward and L.E. Watson, eds.: In: J.W. Kadereit and C. Jeffrey, Compositae, In: Flowering Plants· Eudicots, Springer: Berlin, Heidelberg, pp. 61-588 (2007).
  20. N. Devos, N.P. Barker, B. Nordenstam and L. Mucina, Taxon, 59, 57 (2010); https://doi.org/10.1002/tax.591007
  21. B. Nordenstam, V.R. Clark, N. Devos and N.P. Barker, S. Afr. J. Bot., 75, 145 (2009); https://doi.org/10.1016/j.sajb.2008.10.003
  22. S.W. Odeyemi, A.J. Afolayan and G. Bradley, Conference: The 25th Congress of the South African Society of Biochemistry and Molecular Biology, East London International Convention Centre, South Africa University of Fort Hare (2016).
  23. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. RiceEvans, Free Radic. Biol. Med., 26, 1231 (1999); https://doi.org/10.1016/S0891-5849(98)00315-3
  24. J.A. Badmus, T.O. Adedosu, J.O. Fatoki, V.A. Adegbite, O.A. Adaramoye and OA. Odunola, Acta Pol. Pharm., 68, 23 (2011).
  25. Clinical Laboratory Standards Institute (CLSI), Approved Standard: M7-A6, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, Clinical Laboratory Standards Institute, Wayne, PA, USA, edn 14 (2014).
  26. P. Christofilogiannis, Aquaculture, 196, 297 (2001); https://doi.org/10.1016/S0044-8486(01)00542-7
  27. G.S. Bonjar, Asian J. Plant Sci., 3, 82 (2003); https://doi.org/10.3923/ajps.2004.82.86
  28. C.M. Kibiti, Ph.D. Thesis, University of Fort Hare (2016).
  29. S. Maiti, S. Raju, K. Geetha and K. Mandal, Good Agricultural Practices for Patchouli, Geranium and Lemongrass. Gujarat, India: National Research Centre for Medicinal and Aromatic Plants, pp 16-17 (2006).
  30. R. Tundis, F. Menichini, M. Bonesi, F. Conforti, G. Statti, F. Menichini and M.R. Loizzo, Lebensm. Wiss. Technol., 53, 370 (2013); https://doi.org/10.1016/j.lwt.2013.02.013
  31. J.G. Longhi, E. Perez, J.J. Lima and L.M. Cândido, Braz. J. Pharm. Sci., 47, 535 (2011); https://doi.org/10.1590/S1984-82502011000300011
  32. A. Guerrini, G. Sacchetti, D. Rossi, G. Paganetto, M. Muzzoli, E. Andreotti, M. Tognolini, M.E. Maldonado and R. Bruni, Environ. Toxicol. Pharmacol., 27, 39 (2009); https://doi.org/10.1016/j.etap.2008.08.002
  33. W. Wang, N. Wu, Y.G. Zu and Y.J. Fu, Food Chem., 108, 1019 (2008); https://doi.org/10.1016/j.foodchem.2007.11.046
  34. A.C. Silva, P.M. Lopes, M.M. Azevedo, D.C. Costa, C.S. Alviano and D.S. Alviano, Molecules, 17, 6305 (2012);https://doi.org/10.3390/molecules17066305
  35. R.A. Mothana, M.S. Alsaid and N.M. Al-Musayeib, Molecules, 16, 5149 (2011); https://doi.org/10.3390/molecules16065149
  36. S. Santoyo, S. Cavero, L. Jaime, E. Ibanez, F.J. Senorans and G. Reglero, J. Food Prot., 68, 790 (2005);https://doi.org/10.4315/0362-028X-68.4.790
  37. S.F. van Vuuren, A.M. Viljoen, T. Ozek, B. Demirci and K.H. Baser, S. Afr. J. Bot., 73, 441 (2007); https://doi.org/10.1016/j.sajb.2007.03.010
  38. F. Ayoughi, M. Barzegar, M.A. Sahari and H. Naghdibadi, J. Agric. Sci. Technol., 13, 79 (2011).
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