Extraction, Fractionation and Pharmacological Activity of Dipteracanthus prostratus (Poir) Nees

Abstract

Whole plant of Dipteracanthus prostratus (poir) nees were subjected to extraction and further fractionation to obtain isolated compounds. Different concentrations of methanolic extract were subjected to analgesic, antiinflammatory and wound healing assay by hotplate, paw oedema and excision wound model methods respectively. The methanolic extracts showed dose dependent analgesic, antiinflammatory and wound healing property as compared to standards. The extracts showed significant results in all three assays with increasing concentration. The phytochemical screenings confirm the presence of triterpenoids, flavonoids, alkaloids, phytosterols glycosides and carbohydrates, which are responsible for the analgesic, antiinflammatory and wound healing activity.