TY - JOUR AU - Mushtaq, Muhammad AU - Anwer, Nadeem AU - Asim Waqar, Muhammad AU - Latif, Shabanem AU - Ali Shahid, Shaukat AU - Azam, Adeela PY - 2013/11/12 Y2 - 2024/03/29 TI - Antioxidant, Antimicrobial Potential and Phytochemical Attributes of Impatiens edgeworthii JF - Asian Journal of Chemistry JA - ajc VL - 25 IS - 17 SE - Articles DO - 10.14233/ajchem.2013.15362 UR - https://asianpubs.org/index.php/ajchem/article/view/25_18_81 SP - 9800-9804 AB - <p style="text-align: justify;">In this work, we investigated the availability of antioxidant, antimicrobial and phytochemical agents native to <em>Impatiens edgeworthii</em> in various extraction solvents. The fractional extracts obtained for different solvents showed substantial levels total phenolic (124-430 mg/g GAE), anti-radical potential (32-89 %) and total antioxidant capacity 0.3-0.8 <em>versus</em> gallic acid and butylated hydroxy toluene having total antioxidant capacity value 0.85-1.2. Phytochemical analysis confirmed the presence of flavonoids, sugars, alkaloids and saponins. <em>in vitro</em> disc diffusion assay showed that all the extracts of <em>I. edgeworthii</em> have the antimicrobial activity comparable with standard antibiotics. Furthermore, among tested solvents (<em>n</em>-hexane, chloroform, ethyl acetate and methanol) ethyl acetate was found to be more effective for the recovery of phytochemicals, phenolics, antioxidants and antimicrobial agents. The results of present study indicate <em>I. edgeworthii</em> is latent source of potential bioactive and might be further explored for the development of chemopreventive drugs and nutraceuticals.</p> ER -