TY - JOUR AU - Shen, Ping PY - 2013/11/12 Y2 - 2024/03/28 TI - Effects of Copper(II) Complexes on the Growth of Escherchia coli by Microcalorimetry JF - Asian Journal of Chemistry JA - ajc VL - 25 IS - 17 SE - Articles DO - 10.14233/ajchem.2013.15576 UR - https://asianpubs.org/index.php/ajchem/article/view/25_18_103 SP - 9897-9900 AB - <p style="text-align: justify;">Copper(II) complexes were synthesized and their effects on the growth of <em>Escherchia coli</em> (<em>E. coli</em>) were studied by microcalorimetry. Based on the power-time curves of <em>Escherchia coli</em> growth under the action of these copper(II) compounds, thermodynamics and kinetic data of metabolism of <em>E. coli</em> were calculated. The results revealed that there were differences in their capacities to inhibit the metabolism of this bacterium. The growth rate constant decreased with increasing concentrations of the copper complexes. Judged from the half-inhibitory concentration (IC<sub>50</sub>) [Cu(phen)<sub>2</sub>]Cl<sub>2</sub>·6H<sub>2</sub>O and [Cu(phen)<sub>3</sub>]Cl<sub>2</sub>·6H<sub>2</sub>O have the strongest antibacterial activity and CuCl<sub>2</sub>·2H<sub>2</sub>O has the weakest antibacterial activity.</p> ER -