@article{Ashok Kumar_Rama Devi_Dubey_2013, title={Green Syntheses of N-Alkyl-2-styrylbenzimidazoles}, volume={25}, url={https://asianpubs.org/index.php/ajchem/article/view/25_18_34}, DOI={10.14233/ajchem.2013.15080}, abstractNote={<p style="text-align: justify;">Simple and green methodologies for the syntheses of 2-styrylbenzimidazoles (<strong>3a-c</strong>) and its N-alkyl derivatives (<strong>7a-i</strong>) have been developed. <em>o</em>-Phenylenediamine (<strong>1</strong>) was condensed with cinnamic acids (<strong>2a-c</strong>) resulting in 2-styrylbenzimidazoles (<strong>3a-c</strong>) using glycerol as a green and efficient solvent. <strong>3</strong> were also prepared alternatively by the condensation of 2-methylbenzimidazole (<strong>4</strong>) with benzaldehydes (<strong>5a-c</strong>) using glycerol as solvent. 2-Styrylbenzimidazoles (<strong>3a-c</strong>) and 2-methylbenzimidazole (<strong>4</strong>) were alkylated independently to obtain N-alkyl-2-styrylbenzimidazole (<strong>7a-i</strong>) and N-alkyl-2-methylbenzimidazole (<strong>6a-c</strong>), respectively using DMS/DES/PhCH<sub>2</sub>Cl applying green methods such as simple physical grinding of reactants in solid phase, treating reactants in PEG-600 as a solvent in solution phase and using microwave irradiation of reactants respectively. Compounds <strong>7a-i</strong> could also be prepared, alternatively, by heating <strong>6a-c </strong>with <strong>5a-c</strong> in glycerol at 180 °C for 3-4 h.</p>}, number={17}, journal={Asian Journal of Chemistry}, author={Ashok Kumar, T. and Rama Devi, B. and Dubey, P.K.}, year={2013}, month={Nov.}, pages={9569–9572} }